Universal Audio have finally released their 64-bit plugins for OSX – at this point only in beta version. They are only recommended for Logic users at present.
The Windows 64-bit versions came out at the end of November 2012, with beta OSX versions promised in December 2012. So they’re only slightly late.
UAD plugins will only run on a choice of various types of UAD host hardware or accelerator cards. They appear in your DAW as typical plugins, but they feature some exquisitely-modeled vintage audio gear.